When The Doctor's Wife was first published in 1864, Mary Elizabeth Braddon was well known for her scandalous bestseller, Lady Audley's Secret. Adultery, death, and the spectacle of female recrimination and suffering are the elements that combine to make The Doctor's Wife a classic women's 'sensation' novel. Yet it is also Braddon's most self-consciously literary work and her rewriting of Madame Bovary. Like Emma Bovary, Braddon's heroine, Isabel Gilbert, is trapped in a marriage to a man incapable of understanding her imaginative life. But Braddon's novel differs vastly from Flaubert's in the nature and consequences of Isabel's 'affair'.