A gifted but troubled physician, Blue Calhoun runs a thriving medical practice from his Nob Hill mansion in San Francisco while raising his son alone after an unthinkable tragedy. Then one day a female fugitive with a gunshot wound appears in Blue's surgery. Even though she holds a pistol aimed at his heart, the desperation in her eyes awakens Blue's compassion. Reluctantly he is drawn to her fragile beauty, her nerves of steel and the mystery surrounding her circumstances.

Isabel Fish-Wooten has spent most of her life on the run, but everything changes when she forces a stranger to save her life. Yet her rescue comes with an unexpected price. As Isabel recovers from her wounds, she finds herself touched by this remarkable man and yearns to reach out to him and his rebellious son.

From danger-filled back alleys to the glittering ballrooms of high society, Isabel and Blue confront the violence and corruption that threatens their new-found passion. Theirs is an unforgettable quest to discover a rare and special love, and the precious gift of a second chance at happiness.