The highly virulent C-virus became a global disaster, but where did the outbreak start? In this prequel to the hit Resident Evil 6 game, the terrifying origins are revealed.

At the prestigious and elite Marhawa High School in Singapore, a female student suffers a horrifying transformation. Called in to investigate, Professor Doug Wright and his nephew Ricky find themselves caught up in a deadly and growing tragedy. As things get rapidly out of hand, Chris Redfield and his team from the Bioterrorism Security Assessment Alliance arrive on the scene, while behind it all a mysterious figure looms.